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Complement C3(β chain) Antibody

Catalog Number:

48019
other_names: Acylation-stimulating protein cleavage product antibody
AHUS5 antibody
ARMD9 antibody
ASP antibody
C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1 antibody
C3 antibody
CO3_HUMAN antibody
Complement C3 a

Amount:

100μg
calculated_mw: 70kDa
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#:P01024

Form of Antibody:

1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

Storage/Stability:

Immunogen:

peptide

Purification:

Immunogen affinity purified

Specificity/Sensitivity:

Applications:

WB

Background:

Human Complement C3 (C3) is synthesized as a single-chain pro-molecule (185 kDa) that tsuffers several posttranslational modifications. Before being a mature protein, C3 is split into beta-chain (70 kDa) and alpha chain (115 kDa) and forms a rare internal thioester bond. C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates.

References:

appl_detail:

WB: 1:1,000



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