1-832-868-1888
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Catalog Number: |
48000 |
| other_names: | Antigen identified by monoclonal antibody R1 antibody CAML1 antibody CD171 antibody CD171 antigen antibody HSAS antibody HSAS1 antibody Hyd antibody L1 antibody L1 cell adhesion molecule antib |
Amount: |
100μg |
| calculated_mw: | 220kDa |
| host_species: | Rabbit |
Price: |
$319 |
Swiss-Prot No: |
Swiss-Prot#:P32004 |
Form of Antibody: |
1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
Storage/Stability: |
|
Immunogen: |
Synthetic peptide (KLH-coupled) corresponding to a region of C-terminal residues of NCAM-L1. |
Purification: |
Peptide affinity purified |
Specificity/Sensitivity: |
|
Applications: |
WB, ICC, IHC, FC |
Background: |
The neural cell adhesion molecule L1 (NCAM-L1) is an immunoglobulin superfamily adhesion molecule that is critical for neural development, involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. Defects in L1CAM are the cause of hydrocephalus due to stenosis of the aqueduct of Sylvius (HSAS). Hydrocephalus is a condition in which abnormal accumulation of cerebrospinal fluid in the brain causes increased intracranial pressure inside the skull. Defects in L1CAM are also the cause of mental retardation, aphasia, shuffling gait, and adducted thumbs syndrome (MASA), a X-linked disorder. |
References: |
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appl_detail: |
WB: 1:500-1:1,000 |
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