ITGB4 Antibody

Catalog Number:

47804

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:P16144
NCBI Gene ID:3691
Gene Accssion:NP_000204

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human ITGB4

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total ITGB4 protein.

Applications:

IHC

Background:

Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

References:

appl_detail:

IHC dilution:1: 20-100

Datasheet PDF