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HBB Antibody

Catalog Number:

47773
other_names: CD113t-C; beta-globin

Amount:

100μg
calculated_mw: 16 kDa
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#:P68871
NCBI Gene ID:3043
Gene Accssion:NP_000509

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human HBB

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total HBB protein.

Applications:

WB, IHC

Background:

The alpha (HBA) and beta (HBB) loci determine the structure of the 2 types of polypeptide chains in adult hemoglobin, Hb A. The normal adult hemoglobin tetramer consists of two alpha chains and two beta chains. Mutant beta globin causes sickle cell anemia. Absence of beta chain causes beta-zero-thalassemia. Reduced amounts of detectable beta globin causes beta-plus-thalassemia. The order of the genes in the beta-globin cluster is 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'.

References:

appl_detail:

WB dilution:1:200-1000
IHC dilution:1: 10-50

Datasheet PDF

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