MANSC1 Antibody

Catalog Number:

47744

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q9H8J5
NCBI Gene ID:54682
Gene Accssion:BC032998

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein of human MANSC1

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total MANSC1 protein.

Applications:

IHC

Background:

MANSC1 (MANSC domain-containing protein 1), also known as LOH12CR3 (Loss of heterozygosity 12 chromosomal region 3 protein), is a 414 amino acid single-pass membrane protein. Expressed throughout the body, MANSC1 contains one MANSC domain and is encoded by a gene that is located on chromosome 12. Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5% of the human genome. A number of skeletal deformities are linked to chromosome 12, including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction.

References:

appl_detail:

IHC dilution:1: 50-300

Datasheet PDF