HLA-E Antibody

Catalog Number:

47738

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:P13747
NCBI Gene ID:3133
Gene Accssion:BC002578

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein of human HLA-E

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total HLA-E protein.

Applications:

IHC

Background:

HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail.

References:

appl_detail:

IHC dilution:1: 50-300

Datasheet PDF