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PDIA5 Antibody

Catalog Number:

47722
other_names: PDIR

Amount:

100μg
calculated_mw: 60 kDa
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q14554
NCBI Gene ID:10954
Gene Accssion:BC001625

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein of human PDIA5

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total PDIA5 protein.

Applications:

WB, IHC

Background:

This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, three catalytically active thioredoxin (TRX) domains, a TRX-like domain, and a C-terminal ER-retention sequence. The N-terminal TRX-like domain is the primary binding site for the major ER chaperone calreticulin and possibly other proteins and substrates as well. Alternative splicing results in multiple protein- and non-protein-coding transcript variants.

References:

appl_detail:

WB dilution:1:1000-5000
IHC dilution:1: 30-150

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