KCNN2 Antibody

Catalog Number:

47688

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q9H2S1
NCBI Gene ID:3781
Gene Accssion:NP_067627

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human KCNN2

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total KCNN2 protein.

Applications:

IHC

Background:

Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. This gene is a member of the KCNN family of potassium channel genes. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. Alternate splicing of this gene results in multiple transcript variants.

References:

appl_detail:

IHC dilution:1: 50-300

Datasheet PDF