PPY Antibody

Catalog Number:

47676

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:P01298
NCBI Gene ID:5539
Gene Accssion:NP_002713

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human PPY

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total PPY protein.

Applications:

WB

Background:

This gene encodes a member of the neuropeptide Y (NPY) family of peptides. The encoded 95 aa preproprotein is synthesized in the pancreatic islets of Langerhans and proteolytically processed to generate two peptide products. These products include the active pancreatic hormone of 36 aa and an icosapeptide of unknown function. This hormone acts as a regulator of pancreatic and gastrointestinal functions and may be important in the regulation of food intake. Plasma level of this hormone has been shown to be reduced in conditions associated with increased food intake and elevated in anorexia nervosa. In addition, infusion of this hormone in obese rodents has shown to decrease weight gain. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

References:

appl_detail:

WB dilution:1:1000-5000

Datasheet PDF