MAPK8IP3 Antibody

Catalog Number:

47674

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q9UPT6
NCBI Gene ID:23162
Gene Accssion:NP_055948

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human MAPK8IP3

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total MAPK8IP3 protein.

Applications:

IHC

Background:

The protein encoded by this gene shares similarity with the product of Drosophila syd gene, required for the functional interaction of kinesin I with axonal cargo. Studies of the similar gene in mouse suggested that this protein may interact with, and regulate the activity of numerous protein kinases of the JNK signaling pathway, and thus function as a scaffold protein in neuronal cells. The C. elegans counterpart of this gene is found to regulate synaptic vesicle transport possibly by integrating JNK signaling and kinesin-1 transport. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

References:

appl_detail:

IHC dilution:1: 40-200

Datasheet PDF