MTIF2 Antibody

Catalog Number:

47646

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:P46199
NCBI Gene ID:4528
Gene Accssion:NP_002444

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human MTIF2

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total MTIF2 protein.

Applications:

IHC

Background:

During the initiation of protein biosynthesis, initiation factor-2 (IF-2) promotes the binding of the initiator tRNA to the small subunit of the ribosome in a GTP-dependent manner. Prokaryotic IF-2 is a single polypeptide, while eukaryotic cytoplasmic IF-2 (eIF-2) is a trimeric protein. Bovine liver mitochondria contain IF-2(mt), an 85-kD monomeric protein that is equivalent to prokaryotic IF-2. The predicted 727-amino acid human protein contains a 29-amino acid presequence. Human IF-2(mt) shares 32 to 38% amino acid sequence identity with yeast IF-2(mt) and several prokaryotic IF-2s, with the greatest degree of conservation in the G domains of the proteins.

References:

appl_detail:

IHC dilution:1: 20-100

Datasheet PDF