HNRNPAB Antibody

Catalog Number:

47634

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q99729
NCBI Gene ID:3182
Gene Accssion:NP_112556

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human HNRNPAB

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total HNRNPAB protein.

Applications:

WB, IHC

Background:

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are produced by RNA polymerase II and are components of the heterogeneous nuclear RNA (hnRNA) complexes. They are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene, which binds to one of the components of the multiprotein editosome complex, has two repeats of quasi-RRM (RNA recognition motif) domains that bind to RNAs. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.

References:

appl_detail:

WB dilution:1:200-1000
IHC dilution:1: 20-100

Datasheet PDF