KAT6A Antibody

Catalog Number:

47627

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q92794
NCBI Gene ID:7994
Gene Accssion:NP_006757

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human KAT6A

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total KAT6A protein.

Applications:

IHC

Background:

This gene encodes a member of the MOZ, YBFR2, SAS2, TIP60 family of histone acetyltransferases. The protein is composed of a nuclear localization domain, a double C2H2 zinc finger domain that binds to acetylated histone tails, a histone acetyl-transferase domain, a glutamate/aspartate-rich region, and a serine- and methionine-rich transactivation domain. It is part of a complex that acetylates lysine-9 residues in histone 3, and in addition, it acts as a co-activator for several transcription factors. Allelic variants of this gene are associated with an autosomal dominant form of cognitive disability. Chromosomal translocations of this gene are associated with acute myeloid leukemia. Alternative splicing results in multiple transcript variants.

References:

appl_detail:

IHC dilution:1: 25-100

Datasheet PDF