GP6 Antibody

Catalog Number:

47582

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q9HCN6
NCBI Gene ID:51206
Gene Accssion:NP_057447

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human GP6

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total GP6 protein.

Applications:

WB, IHC

Background:

This gene encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. The encoded protein is a receptor for collagen and plays a critical role in collagen-induced platelet aggregation and thrombus formation. The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding. Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

References:

appl_detail:

WB dilution:1:200-1000
IHC dilution:1: 50-300

Datasheet PDF