FKBP5 Antibody

Catalog Number:

47556

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q13451
NCBI Gene ID:2289
Gene Accssion:NP_004108

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human FKBP5

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total FKBP5 protein.

Applications:

IHC

Background:

The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.

References:

appl_detail:

IHC dilution:1: 50-300

Datasheet PDF