FAM111B Antibody

Catalog Number:

47538

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q6SJ93
NCBI Gene ID:374393
Gene Accssion:NP_945185

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human FAM111B

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total FAM111B protein.

Applications:

IHC

Background:

This gene encodes a protein with a trypsin-like cysteine/serine peptidase domain in the C-terminus. Mutations in this gene are associated with an autosomal dominant form of hereditary fibrosing poikiloderma (HFP). Affected individuals display mottled pigmentation, telangiectasia, epidermal atrophy, tendon contractures, and progressive pulmonary fibrosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. A paralog of this gene which also has a trypsin‐like peptidase domain, FAM111A, is located only 16 kb from this gene on human chromosome 11q12.1.

References:

appl_detail:

IHC dilution:1: 30-150

Datasheet PDF