ESRP2 Antibody

Catalog Number:

47524

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q9H6T0
NCBI Gene ID:80004
Gene Accssion:NP_079215

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human ESRP2

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total ESRP2 protein.

Applications:

WB, IHC

Background:

mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). Acts by directly binding specific sequences in mRNAs. Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2.

References:

appl_detail:

WB dilution:1:200-1000
IHC dilution:1: 30-150

Datasheet PDF