XPC Antibody

Catalog Number:

47500

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q01831
NCBI Gene ID:7508
Gene Accssion:NP_004619

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human XPC

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total XPC protein.

Applications:

IHC

Background:

The protein encoded by this gene is a key component of the XPC complex, which plays an important role in the early steps of global genome nucleotide excision repair (NER). The encoded protein is important for damage sensing and DNA binding, and shows a preference for single-stranded DNA. Mutations in this gene or some other NER components can result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene.

References:

appl_detail:

IHC dilution:1: 30-150

Datasheet PDF