HMGA1 Antibody

Catalog Number:

47493

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:P17096
NCBI Gene ID:3159
Gene Accssion:NP_665906

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human HMGA1

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total HMGA1 protein.

Applications:

IHC

Background:

This gene encodes a non-histone protein involved in many cellular processes, including regulation of inducible gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of A+T-rich regions in double-stranded DNA. It has little secondary structure in solution but assumes distinct conformations when bound to substrates such as DNA or other proteins. The encoded protein is frequently acetylated and is found in the nucleus. At least seven transcript variants encoding two different isoforms have been found for this gene.

References:

appl_detail:

IHC dilution:1: 50-200

Datasheet PDF