ZIC2 Antibody

Catalog Number:

47487

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:O95409
NCBI Gene ID:7546
Gene Accssion:NP_009060

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human ZIC2 ?

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total ZIC2 ? protein.

Applications:

IHC

Background:

This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. This protein functions as a transcriptional repressor and may regulate tissue specific expression of dopamine receptor D1. Mutations in this gene cause holoprosencephaly type 5. Holoprosencephaly is the most common structural anomaly of the human brain. A polyhistidine tract polymorphism in this gene may be associated with increased risk of neural tube defects. This gene is closely linked to a gene encoding zinc finger protein of the cerebellum 5, a related family member on chromosome 13.

References:

appl_detail:

IHC dilution:1: 50-200

Datasheet PDF