VNN1 Antibody

Catalog Number:

47460

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:O95497
NCBI Gene ID:8876
Gene Accssion:NP_004657

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human VNN1

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total VNN1 protein.

Applications:

IF

Background:

This gene encodes a member of the vanin family of proteins, which share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. This protein, like its mouse homolog, is likely a GPI-anchored cell surface molecule. The mouse protein is expressed by the perivascular thymic stromal cells and regulates migration of T-cell progenitors to the thymus. This gene lies in close proximity to, and in the same transcriptional orientation as, two other vanin genes on chromosome 6q23-q24.

References:

appl_detail:

IF dilution:1:100-500

Datasheet PDF