VMA21 Antibody

Catalog Number:

47459

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q3ZAQ7
NCBI Gene ID:203547
Gene Accssion:NP_001017980

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human VMA21

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total VMA21 protein.

Applications:

IHC, IF

Background:

This gene encodes a chaperone for assembly of lysosomal vacuolar ATPase. Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum. Associates with the V0 complex of the vacuolar ATPase (V-ATPase). MEAX is a childhood-onset disease characterized by progressive vacuolation and atrophy of skeletal muscle. It is inherited in recessive fashion, affecting boys and sparing carrier females. Onset is in childhood, and patients exhibit weakness of the proximal muscles of the lower extremities, progressing slowly to involve other skeletal muscle groups over time.

References:

appl_detail:

IHC dilution:1: 150-500
IF dilution:1:50-200

Datasheet PDF