PTPRS Antibody

Catalog Number:

47432

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q13332
NCBI Gene ID:5802
Gene Accssion:BC029496

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein of human PTPRS

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total PTPRS protein.

Applications:

IHC

Background:

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of multiple Ig-like and fibronectin type III-like domains. Studies of the similar gene in mice suggested that this PTP may be involved in cell-cell interaction, primary axonogenesis, and axon guidance during embryogenesis. This PTP has been also implicated in the molecular control of adult nerve repair. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported.?

References:

appl_detail:

IHC dilution:1: 100-300

Datasheet PDF