PCLAF Antibody

Catalog Number:

47429

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q15004
NCBI Gene ID:9768
Gene Accssion:BC005832

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein of human PCLAF

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total PCLAF protein.

Applications:

IHC

Background:

PCNA-binding protein that acts as a regulator of DNA repair during DNA replication. Following DNA damage, the interaction with PCNA is disrupted, facilitating the interaction between monoubiquitinated PCNA and the translesion DNA synthesis DNA polymerase eta (POLH) at stalled replisomes, facilitating the bypass of replication-fork-blocking lesions. Also acts as a regulator of centrosome number.

References:

appl_detail:

IHC dilution:1: 50-300

Datasheet PDF