POLD2 Antibody

Catalog Number:

47414

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:P49005
NCBI Gene ID:5425
Gene Accssion:BC000459

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein of human POLD2

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total POLD2 protein.

Applications:

WB, IHC

Background:

This gene encodes the 50-kDa catalytic subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein is required for the stimulation of DNA polymerase delta activity by the processivity cofactor proliferating cell nuclear antigen (PCNA). Expression of this gene may be a marker for ovarian carcinomas. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5.

References:

appl_detail:

WB dilution:1:1000-5000
IHC dilution:1: 50-300

Datasheet PDF