RBFOX2 Antibody

Catalog Number:

47392

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:O43251
NCBI Gene ID:23543
Gene Accssion:BC013115

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein of human RBFOX2

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total RBFOX2 protein.

Applications:

IHC

Background:

This gene is one of several human genes similar to the C. elegans gene Fox-1. This gene encodes an RNA binding protein that is thought to be a key regulator of alternative exon splicing in the nervous system and other cell types. The protein binds to a conserved UGCAUG element found downstream of many alternatively spliced exons and promotes inclusion of the alternative exon in mature transcripts. The protein also interacts with the estrogen receptor 1 transcription factor and regulates estrogen receptor 1 transcriptional activity. Multiple transcript variants encoding different isoforms have been found for this gene.

References:

appl_detail:

IHC dilution:1: 50-300

Datasheet PDF