NTAN1 Antibody

Catalog Number:

47376

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q96AB6
NCBI Gene ID:123803
Gene Accssion:BC017336

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein of human NTAN1

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total NTAN1 protein.

Applications:

IHC

Background:

The protein encoded by this gene functions in a step-wise process of protein degradation through the N-end rule pathway. This protein acts as a tertiary destabilizing enzyme that deamidates N-terminal L-Asn residues on proteins to produce N-terminal L-Asp. L-Asp substrates are subsequently conjugated to L-Arg, which is recognized by specific E3 ubiquitin ligases and targeted to the proteasome. Pseudogenes of this gene are located on the long arms of chromosomes 8, 10 and 12. Alternative splicing results in multiple transcript variants that encode different protein isoforms.

References:

appl_detail:

IHC dilution:1: 50-300

Datasheet PDF