FUNDC2 Antibody

Catalog Number:

47355

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q9BWH2
NCBI Gene ID:65991
Gene Accssion:BC000255

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein of human FUNDC2

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total FUNDC2 protein.

Applications:

IHC

Background:

FUNDC2 (FUN14 domain-containing protein 2), also known as HCC-3 (cervical cancer proto-oncogene 3 protein), HCBP6 (hepatitis C virus core-binding protein 6) or DC44, is a 189 amino acid protein belonging to the FUN14 family. The gene encoding FUNDC2 maps to human chromosome Xq28. The X and Y chromosomes are the human sex chromosomes. Chromosome X consists of about 153 million base pairs and nearly 1,000 genes. The combination of an X and Y chromosome lead to normal male development while two copies of X lead to normal female development. More than one copy of the X chromosome with a Y chromosome causes Klinefelter's syndrome. A single copy of X alone leads to Turner's syndrome. More than 2 copies of the X chromosome, in the absence of a Y chromosome, is known as Triple X syndrome. Color blindness, hemophilia, and Duchenne muscular dystrophy are well known X chromosome-linked conditions which affect males more frequently as males carry a single X chromosome.

References:

appl_detail:

IHC dilution:1: 50-300

Datasheet PDF