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HIST1H2BN Antibody

Catalog Number:

47345
other_names: H2B/d; H2BFD

Amount:

100μg
calculated_mw: 14 kDa
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q99877
NCBI Gene ID:8341
Gene Accssion:BC011372

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein of human HIST1H2BN

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total HIST1H2BN protein.

Applications:

WB, IHC

Background:

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3.

References:

appl_detail:

WB dilution:1:200-1000
IHC dilution:1: 30-150

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