MPZL1 Antibody

Catalog Number:

47339

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:O95297
NCBI Gene ID:9019
Gene Accssion:BC007881

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein of human MPZL1

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total MPZL1 protein.

Applications:

IHC

Background:

Cell surface receptor, which is involved in signal transduction processes. Recruits PTPN11/SHP-2 to the cell membrane and is a putative substrate of PTPN11/SHP-2. Is a major receptor for concanavalin-A (ConA) and is involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases. Isoform 3 seems to have a dominant negative role; it blocks tyrosine phosphorylation of MPZL1 induced by ConA. Isoform 1, but not isoform 2 and isoform 3, may be involved in regulation of integrin-mediated cell motility.

References:

appl_detail:

IHC dilution:1: 25-100

Datasheet PDF