HIST1H2BK Antibody

Catalog Number:

47334

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:O60814
NCBI Gene ID:85236
Gene Accssion:BC000893

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein of human HIST1H2BK

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total HIST1H2BK protein.

Applications:

IHC

Background:

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-dependent histone that is a member of the histone H2B family. The protein encoded is an antimicrobial protein with antibacterial and antifungal activity. Two transcripts that encode the same protein have been identified for this gene, which is found in the histone microcluster on chromosome 6p21.33.

References:

appl_detail:

IHC dilution:1: 40-200

Datasheet PDF