LPXN Antibody

Catalog Number:

47296

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:O60711
NCBI Gene ID:9404
Gene Accssion:BC019035

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein of human LPXN

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total LPXN protein.

Applications:

IHC

Background:

The product encoded by this gene is preferentially expressed in hematopoietic cells and belongs to the paxillin protein family. Similar to other members of this focal-adhesion-associated adaptor-protein family, it has four leucine-rich LD-motifs in the N-terminus and four LIM domains in the C-terminus. It may function in cell type-specific signaling by associating with PYK2, a member of focal adhesion kinase family. As a substrate for a tyrosine kinase in lymphoid cells, this protein may also function in, and be regulated by, tyrosine kinase activity. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

References:

appl_detail:

IHC dilution:1: 25-100

Datasheet PDF