C8orf4 Antibody

Catalog Number:

47270

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q9NR00
NCBI Gene ID:56892
Gene Accssion:BC020623

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein of human C8orf4

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total C8orf4 protein.

Applications:

IHC

Background:

This gene encodes a small, monomeric, predominantly unstructured protein that functions as a positive regulator of the Wnt/beta-catenin signaling pathway. This protein interacts with a repressor of beta-catenin mediated transcription at nuclear speckles. It is thought to competitively block interactions of the repressor with beta-catenin, resulting in up-regulation of beta-catenin target genes. The encoded protein may also play a role in the NF-kappaB and ERK1/2 signaling pathways. Expression of this gene may play a role in the proliferation of several types of cancer including thyroid cancer, breast cancer and hematological malignancies.

References:

appl_detail:

IHC dilution:1: 50-300

Datasheet PDF