PBXIP1 Antibody

Catalog Number:

47259

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q96AQ6
NCBI Gene ID:57326
Gene Accssion:BC016852

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein of human PBXIP1

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total PBXIP1 protein.

Applications:

IHC

Background:

The protein encoded by this gene interacts with the PBX1 homeodomain protein, inhibiting its transcriptional activation potential by preventing its binding to DNA. The encoded protein, which is primarily cytosolic but can shuttle to the nucleus, also can interact with estrogen receptors alpha and beta and promote the proliferation of breast cancer, brain tumors, and lung cancer. Several transcript variants encoding different isoforms have been found for this gene. More variants exist, but their full-length natures have yet to be determined.

References:

appl_detail:

IHC dilution:1: 30-150

Datasheet PDF