SEPT7 Antibody

Catalog Number:

47243

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q16181
NCBI Gene ID:989
Gene Accssion:BC067264

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein of human SEPT7

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total SEPT7 protein.

Applications:

WB, IHC

Background:

This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19

References:

appl_detail:

WB dilution:1:500-2000
IHC dilution:1: 100-300

Datasheet PDF