UBXN1 Antibody

Catalog Number:

47231

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q04323
NCBI Gene ID:51035
Gene Accssion:BC001372

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Full length fusion protein

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total UBXN1 protein.

Applications:

WB, IHC

Background:

Ubiquitin-binding protein that interacts with the BRCA1-BARD1 heterodimer, and regulates its activity. Specifically binds 'Lys-6'-linked polyubiquitin chains. Interaction with autoubiquitinated BRCA1, leads to inhibit the E3 ubiquitin-protein ligase activity of the BRCA1-BARD1 heterodimer. Component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulum that are retrotranslocated in the cytosol.

References:

appl_detail:

Western blotting:1:500-2000
Immunofluorescence:1: 40-200

Datasheet PDF