TSG101 Antibody

Catalog Number:

47227

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q99816
NCBI Gene ID:7251
Gene Accssion:BC002487

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein of human TSG101

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total TSG101 protein.

Applications:

IHC

Background:

The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression.

References:

appl_detail:

Immunofluorescence:1: 25-100

Datasheet PDF