TRAF4 Antibody

Catalog Number:

47224

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q9BUZ4
NCBI Gene ID:9618
Gene Accssion:BC001769

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein of human TRAF4

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total TRAF4 protein.

Applications:

WB, IHC

Background:

This gene encodes a member of the TNF receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. The encoded protein has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD(P)H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK. Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined.

References:

appl_detail:

Western blotting:1:200-1000
Immunofluorescence:1: 25-100

Datasheet PDF