SLC22A18 Antibody

Catalog Number:

47204

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q96BI1
NCBI Gene ID:5002
Gene Accssion:NP_002546

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human SLC22A18

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total SLC22A18 protein.

Applications:

IHC

Background:

This gene is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. This gene is imprinted, with preferential expression from the maternal allele. Mutations in this gene have been found in Wilms' tumor and lung cancer. This protein may act as a transporter of organic cations, and have a role in the transport of chloroquine and quinidine-related compounds in kidney. Several alternatively spliced transcript variants encoding different isoforms have been described.

References:

appl_detail:

Immunofluorescence:1: 20-100

Datasheet PDF