SGCG Antibody

Catalog Number:

47202

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q13326
NCBI Gene ID:6445
Gene Accssion:NP_000222

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human SGCG

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total SGCG protein.

Applications:

WB

Background:

This gene encodes gamma-sarcoglycan, one of several sarcolemmal transmembrane glycoproteins that interact with dystrophin. The dystrophin-glycoprotein complex (DGC) spans the sarcolemma and is comprised of dystrophin, syntrophin, alpha- and beta-dystroglycans and sarcoglycans. The DGC provides a structural link between the subsarcolemmal cytoskeleton and the extracellular matrix of muscle cells. Defects in the encoded protein can lead to early onset autosomal recessive muscular dystrophy, in particular limb-girdle muscular dystrophy, type 2C (LGMD2C).

References:

appl_detail:

Western blotting:1:200-1000

Datasheet PDF