QARS Antibody

Catalog Number:

47181

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:P47897
NCBI Gene ID:5859
Gene Accssion:BC016634

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein of human QARS

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total QARS protein.

Applications:

IHC

Background:

Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. In metazoans, 9 aminoacyl-tRNA synthetases specific for glutamine (gln), glutamic acid (glu), and 7 other amino acids are associated within a multienzyme complex. Although present in eukaryotes, glutaminyl-tRNA synthetase (QARS) is absent from many prokaryotes, mitochondria, and chloroplasts, in which Gln-tRNA(Gln) is formed by transamidation of the misacylated Glu-tRNA(Gln). Glutaminyl-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family. Alternative splicing results in multiple transcript variants.?

References:

appl_detail:

Immunofluorescence:1: 20-100

Datasheet PDF