POR Antibody

Catalog Number:

47179

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:P16435
NCBI Gene ID:5447
Gene Accssion:BC034277

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein of human POR

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total POR protein.

Applications:

WB, IHC

Background:

This gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome.

References:

appl_detail:

Western blotting:1:200-1000
Immunofluorescence:1: 20-100

Datasheet PDF