IFRD2 Antibody

Catalog Number:

47138

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q12894
NCBI Gene ID:7866
Gene Accssion:BC001676

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein of human IFRD2

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total IFRD2 protein.

Applications:

IHC

Background:

IFRD2 (Interferon-related developmental regulator 2), also known as SKMC15, is a 442 amino acid soluble nuclear protein. IFRD2 is ubiquitously expressed and contains a β-catenin-like repeat, which may indicate an involvement in APC signaling. With 75% homology to IFRD1, IFRD2 may also regulate expression of surface adhesion molecules involved in differentiation and fusion of myogenic satellite cells. Although the gene encoding IFRD2 undergoes overlapping homozygous deletions in many lung cancer cell lines, IFRD2 exhibits no loss-of-function mutations in cancer cells, suggesting a possible role in tumor progression.

References:

appl_detail:

Immunofluorescence:1: 20-100

Datasheet PDF