EHD3 Antibody

Catalog Number:

47094

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q9NZN3
NCBI Gene ID:30845
Gene Accssion:NP_055415

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human EHD3

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total EHD3 protein.

Applications:

WB, IHC

Background:

The Eps15 homology (EH) domain-containing protein family consists of four members, EHD1, EHD2, EHD3, and EHD4. The chromosomal locations of the human EHD genes are as follows: EHD1 maps to 11q13, EHD2 maps to 19q13.3, EHD3 maps to 2p21, and EHD4 maps to 15q11.1 (1-3). The encoded proteins of all EHD family members contain multiple conserved regions, which include an amino-terminal nucleotide-binding consensus site, a bipartite nuclear localization signal, and a carboxy-terminal EH protein-binding domain with an EF-hand motif (3,4). EHD1 is ubiquitously expressed with increased expression in testis (2,3). EHD2, EHD3, and EHD4 have more specific expression with EHD2 highly expressed in heart, EHD3 expressed in brain, kidney, liver, placenta, ovary, and heart, and EHD4 expressed in heart, placenta, and pancreas (1,5,6). The EHD proteins may participate in ligand-induced endocytosis (3-5).

References:

appl_detail:

Western blotting:1:200-1000
Immunofluorescence:1: 20-100

Datasheet PDF