EDEM1 Antibody

Catalog Number:

47091

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q92611
NCBI Gene ID:9695
Gene Accssion:NP_055489

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human EDEM1

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total EDEM1 protein.

Applications:

IHC

Background:

Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-independent manner, probably by forming a complex with SEL1L. It has low mannosidase activity, catalyzing mannose trimming from Man8GlcNAc2 to Man7GlcNAc2.

References:

appl_detail:

Immunofluorescence:1: 20-100

Datasheet PDF