EBF2 Antibody

Catalog Number:

47090

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q9HAK2
NCBI Gene ID:64641
Gene Accssion:NP_073150

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human EBF2

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total EBF2 protein.

Applications:

WB

Background:

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, is expressed in a variety of tissues with the highest levels in pancreas and brain, and is localized in the nucleus.

References:

appl_detail:

Western blotting:1:500-2000

Datasheet PDF