DR1 Antibody

Catalog Number:

47078

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q01658
NCBI Gene ID:1810
Gene Accssion:NP_001929

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human DR1

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total DR1 protein.

Applications:

IHC

Background:

This gene encodes a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. The encoded protein is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. This protein contains a histone fold motif at the amino terminus, a TBP-binding domain, and a glutamine- and alanine-rich region. The binding of DR1 repressor complexes to TBP-promoter complexes may establish a mechanism in which an altered DNA conformation, together with the formation of higher order complexes, inhibits the assembly of the preinitiation complex and controls the rate of RNA polymerase II transcription.?

References:

appl_detail:

Immunofluorescence:1: 20-100

Datasheet PDF