DNTT Antibody

Catalog Number:

47072

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:P04053
NCBI Gene ID:1791
Gene Accssion:BC012920

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein of human DNTT

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total DNTT protein.

Applications:

WB, IHC

Background:

This gene is a member of the DNA polymerase type-X family and encodes a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. In vivo, the encoded protein is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.

References:

appl_detail:

Western blotting:1:200-1000
Immunofluorescence:1: 20-100

Datasheet PDF