DNAJC8 Antibody

Catalog Number:

47068

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:O75937
NCBI Gene ID:22826
Gene Accssion:NP_055095

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human DNAJC8

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total DNAJC8 protein.

Applications:

IHC

Background:

The DnaJ family is one of the largest of all chaperone families and has evolved with diverse cellular localization and functions. Presence of a J domain defines a protein as a member of the DnaJ family. DnaJ heat shock induced proteins are derived from Escherichia coli and are under the control of the htpR regulatory protein. DnaJ proteins play a critical role in the HSP 70 chaperone machine by interacting with HSP 70 to stimulate ATP hydrolysis. DnaJ proteins contain cysteine rich regions that are composed of zinc fingers, which form a peptide binding domain responsible for the chaperone function. DnaJ proteins are important mediators of proteolysis and are involved in the regulation of protein degradation, exocytosis and endocytosis. DnaJC8 (DnaJ (Hsp 40) homolog, subfamily C, member 8), also known as SPF31 or HSPC331, is a 253 amino acid protein that is suggested to have a potential role as a cochaperone in RNA processing-related processes.

References:

appl_detail:

Immunofluorescence:1: 20-100

Datasheet PDF