DMGDH Antibody

Catalog Number:

47065

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q9UI17
NCBI Gene ID:29958
Gene Accssion:NP_037523

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human DMGDH

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total DMGDH protein.

Applications:

IHC

Background:

This gene encodes an enzyme involved in the catabolism of choline, catalyzing the oxidative demethylation of dimethylglycine to form sarcosine. The enzyme is found as a monomer in the mitochondrial matrix, and uses flavin adenine dinucleotide and folate as cofactors. Mutation in this gene causes dimethylglycine dehydrogenase deficiency, characterized by a fishlike body odor, chronic muscle fatigue, and elevated levels of the muscle form of creatine kinase in serum. Alternative splicing results in multiple transcript variants.

References:

appl_detail:

Immunofluorescence:1: 25-100

Datasheet PDF